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Top 100 Latest Research Topics in Molecular Biology 2024 [Updated]

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Top 100 Latest Research Topics in Molecular Biology

So, are you thinking, what are some of the hottest research topics in molecular biology right now? Here is a list of current research topics in molecular biology:

• The part of non-histone proteins in chromosome building and function during mitosis.
• Restoration of the fission yeast Cdc42 cell-polarity component via the Sty1 p38 stress-activated protein kinase pathway.
• CRISPR and gene editing
• Gradient sensing: Engineering yeast love affair.
• How to make a static cytokinetic channel out of spreading excitable waves.
• Curvature-driven positioning of Turing patterns on phase-separating curved membranes.
• Activator-inhibitor coupling between Rho signaling and actin assembly makes the cell cortex an excitable medium.
• The meiotic spindle and chromosomes in oocytes.
• The molecular mechanisms underlying microtubule nucleation.
• The regulation of cell polarity, in a systems context, under both normal and stress conditions.
• Nuclear envelope transmembrane protein regulation of tissue specific genome group in differentiation and disease.
• Stem cell research
• What is the molecular basis for the establishment and maintenance of CENP-A nucleosomes at centromeres?
• How do the outer kinetochore microtubule binding components such as the Ska and Ndc80 complexes cooperate to facilitate spindle driven chromosome segregation?
• How CPC, a key player required for eliminating incorrect kinetochore-microtubule attachment is targeted to   the kinetochore? 
• Cystic fibrosis.
• Biochemical analysis of a restriction enzyme;
• Calculating the activity of alkaline phosphatase.
• Measuring the selection coefficient of yeast expressing Xenopus TFIIIA.
• Measuring plasmid loss in bacteria.
• Drug delivery
• Measuring the mutagenic effects of ethidium bromide.
• Measuring the mutagenic effects of UV light.
• Cancer cell research
• Measuring effect of plasmid size on transformation efficiency.
• Exploring bacterial transformation conditions.
• Using PCR to compare ribosomal RNA from Different Organisms.
• Chemo-enzymatic Synthesis and Potential Applications of Novel Heterobicyclic Alkaloids.
• Evolving an enzymatic toolbox to make complex modified peptides.
• Genome mining of novel bacterial carbazole natural products from new bacterial strains.
• Biological suggestions of genetic variation in rice for mycorrhizal colonization.
• Physiological and molecular characterization of altered root hydraulic properties in rice due to allelic variation or genetic manipulation of plasma membrane intrinsic proteins (PIPs, a class of aquaporins).
• RNA interference (RNAi)
• Determination of the most appropriate cell sources and harvest methods for in vitro culturing of pig meat.
• Monoclonal antibodies.
• Investigating the potential of novel mimetic molecules to modulate the microphage polarization.
• DNA synthesis
• Novel regulation of platelet-endothelial crosstalk in settings of vascular disease.
• Developing method to rationally design anti-cancer drug combinations.
• The role of non-histone proteins in chromosome structure and function during mitosis.
• Unloading of homologous recombination factors is required for restoring double-stranded DNA at damage repair loci.
• Aneuploidy as a mechanism of adaptation to telomerase insufficiency.
• When there is not enough telomerase: telomerase insufficiency and genome integrity.
• Proteolysis-dependent regulation of telomerase catalytic subunit.
• Molecular pathways that coordinate telomere maintenance and DNA repair machineries.
• Structural evidence for Scc4-dependent localization of cohesion loading.
• The kinetochore controls crossover recombination during meiosis.
• Quantitative cross-linking/mass- spectrometry reveals subtle protein conformational changes.
• Nuclear envelope transmembrane protein regulation of tissue specific genome organization in differentiation and disease
• Investigating the molecular mechanisms of parasite-host interaction between the green alga pluvialis and its parasitic fungus P. sedebokerense .
• Novel antimicrobial peptides from fish blood.
• Bacteriophages – Applications for Biocontrol.
• XenoImport – Towards expanding natural metabolism.
• Alternative splicing, intrinsically disordered regions and higher-order complex formation.
• Transcriptomics and structural bioinformatics of ion channels.
• 3 and its chaperones in the nervous system.
• Role of the SWI/SNF complex in the nervous system.
• Cytokines & growth factors.

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